KYAT1

Across TCGA cell cohorts, KYAT1 protein abundance is significantly associated with the go_rna of many other GO terms, with 634 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KYAT1-associated GO terms across cancer lineages are Response to ether, Thymidine biosynthetic process, and 2'-deoxyribonucleoside biosynthetic process. Each is linked with KYAT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both KYAT1-to-partner and partner-to-KYAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to ether grouped by KYAT1-low versus KYAT1-high in BONE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KYAT1→partner) and Y-score (partner→KYAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to ether →	+0.151	+1.143	<.001	.003	3	4
BONE	Thymidine biosynthetic process →	+0.099	+1.143	.002	.003	3	4
BONE	2'-deoxyribonucleoside biosynthetic process →	+0.099	+1.143	.002	.003	3	4
BONE	Pyrimidine deoxyribonucleoside biosynthetic process →	+0.099	+1.143	.002	.003	3	4
LUNG_SCLC	Surfactant homeostasis →	-0.275	-0.925	<.001	.003	3	3
BLOOD_Leukemia	Response to interleukin-2 →	-0.277	-1.345	.009	.008	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 634 associations by consensus.

Response to ether by KYAT1 expression — BONE

Explore this box plot interactively →