KY

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KY RNA expression is significantly associated with the protein abundance of many other proteins, with 10,174 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KY-associated proteins across cancer lineages are CYFIP2, HCLS1_S275, and NCOA7_S211. Each is linked with KY in more than 3 cancer types. Because this analysis shows association rather than direction, both KY-to-partner and partner-to-KY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KY versus CYFIP2 in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KY→partner) and Y-score (partner→KY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACCYFIP2 →+0.437+0.417<.001<.00134
PDACHCLS1_S275 →-0.745-0.350<.001<.00134
PDACNCOA7_S211 →-0.425-0.364.001.00233
BRCAUSP16 →-0.176-0.215<.001.00233
PDACRPL9 →-0.296-0.360<.001<.00133
PDACSART1_S598 →-0.656-0.283.001.00733
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,174 associations by consensus.

KY vs CYFIP2 — PDAC

Per-sample scatter of KY vs CYFIP2 in PDAC (Pearson r = 0.45).

Explore this scatter interactively →

Exploration