KY

Across TCGA cell cohorts, KY RNA expression is significantly associated with the go_rna of many other GO terms, with 916 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KY-associated GO terms across cancer lineages are Regulation of G1/S transition of mitotic cell cycle, Regulation of type I interferon-mediated signaling pathway, and Post-translational protein targeting to membrane, translocation. Each is linked with KY in more than 5 cancer types. Because this analysis shows association rather than direction, both KY-to-partner and partner-to-KY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G1/S transition of mitotic cell cycle grouped by KY-low versus KY-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KY→partner) and Y-score (partner→KY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of G1/S transition of mitotic cell cycle →	+0.045	+0.058	.002	.009	3	6
PANCREAS	Regulation of type I interferon-mediated signaling pathway →	+0.087	+0.089	<.001	.002	3	6
BLOOD_Leukemia	Post-translational protein targeting to membrane, translocation →	+0.084	+0.382	.001	.007	3	6
SOFT_TISSUE	Negative regulation of calcineurin-mediated signaling →	+0.117	+0.296	<.001	.007	3	5
LARGE_INTESTINE	Regulation of cytokine-mediated signaling pathway →	+0.035	+0.032	.001	.003	3	5
LARGE_INTESTINE	Cerebral cortex radially oriented cell migration →	+0.107	+0.046	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 916 associations by consensus.

Regulation of G1/S transition of mitotic cell cycle by KY expression — PANCREAS

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