KRTCAP3

Across TCGA patient cohorts, KRTCAP3 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTCAP3-associated genes across cancer lineages are DEFB107B, MIR449B, and RNU1-17P. Each is linked with KRTCAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTCAP3-to-partner and partner-to-KRTCAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB107B grouped by KRTCAP3-low versus KRTCAP3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTCAP3→partner) and Y-score (partner→KRTCAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DEFB107B →	+0.239	+7.954	<.001	.008	3	1
HNSC	MIR449B →	+0.323	+7.954	<.001	.008	3	1
UCEC	RNU1-17P →	+0.373	+3.520	<.001	.006	3	1
UCEC	VN1R8P →	+0.138	+3.329	.009	.004	3	1
UCEC	LINC01941 →	+0.058	+4.923	<.001	.002	3	1
UCEC	B3GNTL1P1 →	+0.247	+3.253	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

DEFB107B by KRTCAP3 expression — HNSC

Explore this box plot interactively →