KRTAP9-4

Across TCGA patient cohorts, KRTAP9-4 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP9-4-associated genes across cancer lineages are Rab25, MIG-6, and MSH2. Each is linked with KRTAP9-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP9-4-to-partner and partner-to-KRTAP9-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab25 grouped by KRTAP9-4-low versus KRTAP9-4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP9-4→partner) and Y-score (partner→KRTAP9-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab25 →	-0.482	-3.321	.005	.010	3	2
UCEC	MIG-6 →	+0.126	+2.183	.015	.035	3	1
UCEC	MSH2 →	-0.266	-2.990	.027	.036	3	1
UCEC	N-Cadherin →	+0.290	+2.817	.008	.036	3	1
UCEC	Notch1 →	+0.225	+2.817	.002	.036	3	1
UCEC	VHL →	-0.955	-3.000	.007	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Rab25 by KRTAP9-4 expression — UCEC

Explore this box plot interactively →