KRTAP9-4

Across TCGA pan-cancer cohorts, KRTAP9-4 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated KRTAP9-4 data layer compared with 8 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher KRTAP9-4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRTAP9-4 expression acts as an unfavorable survival marker, although some lineages such as KIRP and LUSC show a favorable association.

KICH, SKCM, and LUAD are the cancer types where KRTAP9-4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
SKCM	OS	Tertile	All	0.236	0.363	<.001	78	view →
LUAD	OS	Tertile	All	0.286	0.793	<.001	72	view →
LIHC	OS	Tertile	All	0.179	0.786	<.001	57	view →
ACC	OS	Tertile	All	0.214	0.802	.002	45	view →
ESCA	DFS	Tertile	II,III,IV	0.125	0.838	.006	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
KIRC	OS	Tertile	All	0.705	0.886	.004	24	view →
SCLC	DFS	Tertile	III,IV	0.137	0.756	.025	18	view →
KIRP	DFS	Tertile	III,IV	1.000	0.335	.024	15	view →
LUSC	DFS	Tertile	II,III,IV	0.778	0.361	.023	12	view →
STAD	DFS	Tertile	IV	0.160	0.402	.044	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

KRTAP9-4–KICH (DFS)

Open the KICH breakdown →