KRTAP9-4

Across TCGA cell cohorts, KRTAP9-4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRTAP9-4-associated genes across cancer lineages are TNP1, CIBAR2, and FIGLA. Each is linked with KRTAP9-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP9-4-to-partner and partner-to-KRTAP9-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by KRTAP9-4-low versus KRTAP9-4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP9-4→partner) and Y-score (partner→KRTAP9-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.160	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CIBAR2 →	+0.348	+4.273	<.001	.006	3	1
LARGE_INTESTINE	FIGLA →	+0.053	+4.415	<.001	.007	3	1
LARGE_INTESTINE	KCTD8 →	+0.255	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TNP1 by KRTAP9-4 expression — LARGE_INTESTINE

Explore this box plot interactively →