Across TCGA pan-cancer cohorts, KRTAP9-1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KRTAP9-1’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where KRTAP9-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP9-1 is over-expressed in tumor.
LUAD and LUSC are the cancer types where KRTAP9-1 tumor–normal differential expression is most reproducible.