Across TCGA pan-cancer cohorts, KRTAP8-2P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KRTAP8-2P’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where KRTAP8-2P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP8-2P is over-expressed in tumor.
BLCA and THCA are the cancer types where KRTAP8-2P tumor–normal differential expression is most reproducible.