KRTAP5-AS1

Across TCGA pan-cancer cohorts, KRTAP5-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated KRTAP5-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher KRTAP5-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRTAP5-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UVM show a favorable association.

MESO, HNSC, and UVM are the cancer types where KRTAP5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	III,IV	0.289	0.531	.001	96	view →
HNSC	OS	Tertile	III,IV	0.837	0.689	.007	44	view →
UVM	OS	Quartile	All	1.000	0.796	.018	38	view →
ACC	DFS	Tertile	All	0.246	0.569	.005	32	view →
ESCA	OS	Median	II,III,IV	0.379	0.612	.009	27	view →
KIRC	DFS	Median	IV	0.637	0.243	.002	20	view →
BRCA	OS	Quartile	IV	0.298	1.000	.007	18	view →
LUAD	DFS	Quartile	IV	0.500	0.938	.012	16	view →
COAD	OS	Quartile	All	0.389	0.725	.012	14	view →
THCA	DFS	Tertile	IV	0.490	1.000	.007	12	view →
KIRP	OS	Tertile	II,III,IV	0.962	0.751	.010	12	view →
SARC	DFS	Quartile	All	0.483	0.235	.003	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

KRTAP5-AS1–MESO (DFS)

Open the MESO breakdown →