KRTAP5-AS1

Across TCGA pan-cancer cohorts, KRTAP5-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of KRTAP5-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where KRTAP5-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types KRTAP5-AS1 is over-expressed in tumor, although a few such as KIRC and LUSC show the opposite, repressed pattern.

KIRC, LUSC, and COAD are the cancer types where KRTAP5-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP5-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	−0.387	<.001	10	view →
LUSC	Female	II,III,IV	−0.841	<.001	7	view →
COAD	Male	All	+0.619	.001	6	view →
BRCA	All	All	+0.602	<.001	6	view →
LUAD	Female	All	+0.495	<.001	6	view →
KICH	Female	All	+1.187	<.001	5	view →
STAD	Male	All	+0.634	<.001	4	view →
LIHC	All	All	+0.305	<.001	4	view →
THCA	All	All	+0.295	<.001	4	view →
CHOL	All	All	+1.004	.002	3	view →
UCEC	All	All	+0.672	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

KRTAP5-AS1–KIRC

Open the KIRC breakdown →