KRTAP5-9

Across TCGA pan-cancer cohorts, KRTAP5-9 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KRTAP5-9 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KRTAP5-9 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated KRTAP5-9 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, SCLC, and LUAD are the cancer types where KRTAP5-9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.633	.018	16	view →
SCLC	DFS	Median	All	0.164	0.625	.018	12	view →
LUAD	OS	Median	All	0.338	0.834	.004	11	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
LUSC	OS	Median	All	0.180	0.675	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KRTAP5-9–UCEC (DFS)

Open the UCEC breakdown →