KRTAP5-7

Across TCGA pan-cancer cohorts, KRTAP5-7 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of KRTAP5-7’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where KRTAP5-7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP5-7 is over-expressed in tumor, although a few such as READ and KIRP show the opposite, repressed pattern.

KICH, BRCA, and LIHC are the cancer types where KRTAP5-7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP5-7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	+0.846	<.001	7	view →
BRCA	All	II,III,IV	+0.116	.003	6	view →
LIHC	All	All	+0.140	.004	3	view →
READ	Male	All	−0.090	.023	2	view →
STAD	All	All	+0.077	.011	2	view →
KIRP	All	All	−0.052	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

KRTAP5-7–KICH

Open the KICH breakdown →