Across TCGA patient cohorts, KRTAP5-2 mutation is significantly associated with the RNA expression of many other genes, with 413 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP5-2-associated genes across cancer lineages are RNU6-492P, RNU6-289P, and AQP7P4. Each is linked with KRTAP5-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-2-to-partner and partner-to-KRTAP5-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-2→partner) and Y-score (partner→KRTAP5-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	2
LUAD	RNU6-289P →	+0.334	+7.930	<.001	.008	3	2
SKCM	AQP7P4 →	+0.066	+3.422	<.001	.006	3	2
BRCA	MIR6853 →	+0.242	+8.057	<.001	.005	3	1
BRCA	OR2AG1 →	+0.108	+7.459	<.001	<.001	3	1
UCEC	CTF1 →	+0.872	+3.332	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 413 associations by consensus.

Exploration

KRTAP5-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-2 data types