Across TCGA patient cohorts, KRTAP5-2 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP5-2-associated genes across cancer lineages are PDCD4, eEF2, and Rictor_pT1135. Each is linked with KRTAP5-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-2-to-partner and partner-to-KRTAP5-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-2→partner) and Y-score (partner→KRTAP5-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.698	-2.990	.006	.036	3	2
UCEC	eEF2 →	+0.442	+3.169	.024	.020	3	1
UCEC	Rictor_pT1135 →	-0.126	-3.169	.025	.020	3	1
UCEC	VHL →	-1.169	-3.169	.001	.020	3	1
UCEC	ETS-1 →	+0.369	+3.169	.034	.020	2	1
UCEC	4E-BP1_pT37_T46 →	-0.722	-3.169	<.001	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

KRTAP5-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-2 data types