Across TCGA cell cohorts, KRTAP5-2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRTAP5-2-associated genes across cancer lineages are OR1L6, OR13C8, and KRTAP19-3. Each is linked with KRTAP5-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-2-to-partner and partner-to-KRTAP5-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-2→partner) and Y-score (partner→KRTAP5-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR1L6 →	+0.019	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.032	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	KRTAP19-3 →	+0.181	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR10G4 →	+0.012	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

KRTAP5-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-2 data types