Across TCGA patient cohorts, KRTAP5-1 mutation is significantly associated with the RNA expression of many other genes, with 123 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP5-1-associated genes across cancer lineages are H2AB3, MRPS21P8, and IFNA12P. Each is linked with KRTAP5-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-1-to-partner and partner-to-KRTAP5-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-1→partner) and Y-score (partner→KRTAP5-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	H2AB3 →	+0.099	+7.930	<.001	.008	3	2
SKCM	MRPS21P8 →	+0.151	+4.385	<.001	.008	3	2
SKCM	IFNA12P →	+0.093	+4.282	<.001	.009	3	1
SKCM	HNRNPA1P29 →	+0.052	+3.913	<.001	.006	3	1
SKCM	RAC1P7 →	+0.112	+5.039	<.001	.003	3	1
SKCM	VN1R31P →	+0.050	+4.282	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 123 associations by consensus.

Exploration

KRTAP5-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-1 data types