Q-omics provides the consensus-scored IFNA12P profile across patient tissues and cancer cell-line models. IFNA12P expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in PAAD. Among the 18 cancer types available for tumor–normal comparison, IFNA12P is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, IFNA12P RNA expression shows 8,566 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight PAAD, THCA, and GBM as cancer lineages where IFNA12P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for IFNA12P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes IFNA12P survival associations across molecular data types. IFNA12P RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible IFNA12P RNA expression–survival associations across cancer types. High IFNA12P expression shows unfavorable associations in PAAD, UCEC, READ, HNSC, LAML and LUSC. The PAAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify PAAD as the clearest survival context for IFNA12P RNA expression.
This table summarizes IFNA12P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for IFNA12P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. IFNA12P shows higher tumor expression in THCA. The THCA box plot shows higher IFNA12P RNA expression in tumor versus normal tissue (log2 FC = +0.014, t-test p = .016).
This table shows molecular features associated with IFNA12P in patient tissues and cancer cell lines. In patient samples, IFNA12P shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
