Across TCGA cell cohorts, KRTAP4-8 mutation is significantly associated with the mutation status of many other genes, with 59 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRTAP4-8-associated genes across cancer lineages are CDH13, ELOA2, and ETFRF1. Each is linked with KRTAP4-8 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-8-to-partner and partner-to-KRTAP4-8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-8→partner) and Y-score (partner→KRTAP4-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CDH13 →	+6.014	+6.014	.001	.001	1	2
BLOOD_Lymphoma	ELOA2 →	+5.014	+5.584	.003	.003	1	1
LARGE_INTESTINE	ETFRF1 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	DIO1 →	+5.523	+5.523	.003	.003	1	1
LARGE_INTESTINE	SCAMP4 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	POLR2M →	+4.523	+5.087	.006	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Exploration

KRTAP4-8 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-8 data types