KRTAP4-7

Across TCGA patient cohorts, KRTAP4-7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,927 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRTAP4-7-associated GO terms across cancer lineages are Spliceosomal complex assembly, mRNA export from nucleus, and Positive regulation of intrinsic apoptotic signaling pathway. Each is linked with KRTAP4-7 in more than 5 cancer types. Because this analysis shows association rather than direction, both KRTAP4-7-to-partner and partner-to-KRTAP4-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal complex assembly grouped by KRTAP4-7-low versus KRTAP4-7-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-7→partner) and Y-score (partner→KRTAP4-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Spliceosomal complex assembly →	+0.118	+0.043	<.001	<.001	3	6
STAD	mRNA export from nucleus →	+0.138	+0.022	<.001	<.001	3	5
STAD	Positive regulation of intrinsic apoptotic signaling pathway →	+0.129	+0.043	<.001	<.001	3	5
STAD	Protein-RNA complex organization →	+0.136	+0.024	<.001	<.001	3	5
STAD	Positive regulation of protein modification by small protein conjugation or removal →	+0.120	+0.024	<.001	<.001	3	5
STAD	DNA integrity checkpoint signaling →	+0.120	+0.037	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,927 associations by consensus.

Spliceosomal complex assembly by KRTAP4-7 expression — STAD

Explore this box plot interactively →