KRTAP4-7

Across TCGA cell cohorts, KRTAP4-7 RNA expression is significantly associated with the go_rna of many other GO terms, with 165 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRTAP4-7-associated GO terms across cancer lineages are Dopamine metabolic process, Positive regulation of developmental pigmentation, and Postsynaptic signal transduction. Each is linked with KRTAP4-7 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP4-7-to-partner and partner-to-KRTAP4-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dopamine metabolic process grouped by KRTAP4-7-low versus KRTAP4-7-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-7→partner) and Y-score (partner→KRTAP4-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Dopamine metabolic process →	-0.097	-0.037	.003	.004	2	3
SKIN	Positive regulation of developmental pigmentation →	-0.082	-0.054	.004	.006	3	2
BONE	Postsynaptic signal transduction →	+0.075	+0.297	.004	.008	3	2
LIVER	Ribonucleoside biosynthetic process →	+0.214	+0.088	<.001	.004	3	2
LARGE_INTESTINE	Export across plasma membrane →	-0.058	-0.227	.005	.006	3	2
LARGE_INTESTINE	Response to L-glutamate →	+0.105	+0.150	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 165 associations by consensus.

Dopamine metabolic process by KRTAP4-7 expression — SKIN

Explore this box plot interactively →