KRTAP4-4

Across TCGA patient cohorts, KRTAP4-4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,881 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRTAP4-4-associated GO terms across cancer lineages are Regulation of exocytosis, Alpha-beta T cell differentiation, and Protein localization to mitochondrion. Each is linked with KRTAP4-4 in more than 5 cancer types. Because this analysis shows association rather than direction, both KRTAP4-4-to-partner and partner-to-KRTAP4-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of exocytosis grouped by KRTAP4-4-low versus KRTAP4-4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-4→partner) and Y-score (partner→KRTAP4-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of exocytosis →	+0.068	+0.098	<.001	<.001	3	6
STAD	Alpha-beta T cell differentiation →	+0.082	+0.074	<.001	<.001	3	6
STAD	Protein localization to mitochondrion →	+0.101	+0.089	<.001	<.001	3	6
STAD	Reactive nitrogen species metabolic process →	+0.086	+0.084	<.001	<.001	3	6
STAD	Amino acid activation →	+0.090	+0.080	<.001	<.001	3	6
STAD	Negative regulation of DNA-binding transcription factor activity →	+0.077	+0.076	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,881 associations by consensus.

Regulation of exocytosis by KRTAP4-4 expression — STAD

Explore this box plot interactively →