KRTAP4-4

Across TCGA patient cohorts, KRTAP4-4 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP4-4-associated genes across cancer lineages are CD4+ Tem, GMP, and Adipocytes. Each is linked with KRTAP4-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-4-to-partner and partner-to-KRTAP4-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by KRTAP4-4-low versus KRTAP4-4-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-4→partner) and Y-score (partner→KRTAP4-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	CD4+ Tem →	+0.039	+5.593	<.001	.040	3	1
LUSC	GMP →	+0.049	+4.264	.019	.024	3	1
UCEC	Adipocytes →	+0.027	+2.507	.009	.022	3	1
UCEC	Neurons →	-0.024	-2.978	.024	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD4+ Tem by KRTAP4-4 expression — PRAD

Explore this box plot interactively →