KRTAP4-4

Across TCGA cell cohorts, KRTAP4-4 RNA expression is significantly associated with the go_rna of many other GO terms, with 174 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KRTAP4-4-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Positive regulation of protein binding, and Negative regulation of gene expression via chromosomal CpG island methylation. Each is linked with KRTAP4-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-4-to-partner and partner-to-KRTAP4-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by KRTAP4-4-low versus KRTAP4-4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-4→partner) and Y-score (partner→KRTAP4-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Maturation of SSU-rRNA →	+0.104	+0.025	.001	.009	3	2
BONE	Positive regulation of protein binding →	-0.139	-0.026	<.001	.009	3	2
BONE	Negative regulation of gene expression via chromosomal CpG island methylation →	+0.137	+0.031	.003	.003	3	2
LUNG_NSCLC_LUAD	Alanyl-tRNA aminoacylation →	+0.073	+0.007	.006	.009	3	2
BONE	Vascular transport →	+0.053	+0.023	<.001	.002	3	1
BONE	Regulation of double-strand break repair via homologous recombination →	+0.080	+0.029	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

Maturation of SSU-rRNA by KRTAP4-4 expression — BONE

Explore this box plot interactively →