Across TCGA patient cohorts, KRTAP4-3 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP4-3-associated genes across cancer lineages are RNU6-1213P, MCHR2, and EIF3JP1. Each is linked with KRTAP4-3 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP4-3-to-partner and partner-to-KRTAP4-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-3→partner) and Y-score (partner→KRTAP4-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1213P →	+0.304	+4.069	<.001	.008	3	3
SCLC	MCHR2 →	+0.351	+4.847	<.001	.009	3	1
COAD	EIF3JP1 →	+0.366	+4.026	<.001	.001	3	1
COAD	TUBAP12 →	+0.229	+3.742	.002	.006	3	1
COAD	MIR6766 →	+0.627	+3.588	<.001	.007	3	1
SKCM	MIR548O2 →	+0.314	+5.328	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

Exploration

KRTAP4-3 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-3 data types