KRTAP4-17P

Across TCGA pan-cancer cohorts, KRTAP4-17P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated KRTAP4-17P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher KRTAP4-17P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRTAP4-17P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

KIRC, BLCA, and KIRP are the cancer types where KRTAP4-17P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.174	0.747	<.001	144	view →
BLCA	DFS	Tertile	III,IV	0.306	0.495	<.001	70	view →
KIRP	OS	Tertile	All	0.425	0.890	<.001	60	view →
LIHC	DFS	Tertile	All	0.183	0.563	<.001	45	view →
TGCT	OS	Tertile	All	0.767	0.968	.002	42	view →
READ	DFS	Quartile	II,III,IV	0.214	0.615	.006	24	view →
ESCA	OS	Tertile	II,III,IV	0.782	0.574	.008	23	view →
LUSC	OS	Median	IV	0.255	0.851	.021	12	view →
THYM	DFS	Tertile	All	0.134	0.871	<.001	9	view →
STAD	DFS	Quartile	III,IV	0.165	0.418	.024	6	view →
SKCM	OS	Tertile	All	0.202	0.345	.020	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

KRTAP4-17P–KIRC (DFS)

Open the KIRC breakdown →