KRTAP4-17P

Across TCGA pan-cancer cohorts, KRTAP4-17P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of KRTAP4-17P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KRTAP4-17P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP4-17P is over-expressed in tumor.

HNSC, LUAD, and LUSC are the cancer types where KRTAP4-17P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP4-17P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	II,III,IV	+0.313	<.001	8	view →
LUAD	All	All	+0.289	<.001	8	view →
LUSC	Female	II,III,IV	+0.697	<.001	6	view →
BLCA	All	All	+0.225	.014	4	view →
STAD	All	All	+0.179	.025	2	view →
COAD	All	All	+0.132	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

KRTAP4-17P–HNSC

Open the HNSC breakdown →