KRTAP4-16

Across TCGA patient cohorts, KRTAP4-16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,440 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRTAP4-16-associated GO terms across cancer lineages are tRNA 5'-leader removal, Pyrimidine ribonucleotide biosynthetic process, and NADH dehydrogenase complex assembly. Each is linked with KRTAP4-16 in more than 4 cancer types. Because this analysis shows association rather than direction, both KRTAP4-16-to-partner and partner-to-KRTAP4-16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 5'-leader removal grouped by KRTAP4-16-low versus KRTAP4-16-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-16→partner) and Y-score (partner→KRTAP4-16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA 5'-leader removal →	+0.079	+0.074	<.001	.002	3	5
STAD	Pyrimidine ribonucleotide biosynthetic process →	+0.070	+0.094	<.001	<.001	2	5
STAD	NADH dehydrogenase complex assembly →	+0.107	+0.059	<.001	<.001	3	4
STAD	Positive regulation of DNA binding →	+0.080	+0.084	<.001	<.001	3	4
STAD	Nucleoside metabolic process →	+0.070	+0.061	<.001	<.001	3	3
STAD	Regulation of long-term synaptic potentiation →	+0.051	+0.085	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,440 associations by consensus.

tRNA 5'-leader removal by KRTAP4-16 expression — STAD

Explore this box plot interactively →