KRTAP4-16

Across TCGA pan-cancer cohorts, KRTAP4-16 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated KRTAP4-16 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher KRTAP4-16 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP4-16 expression acts as an unfavorable survival marker.

BLCA, KIRP, and ACC are the cancer types where KRTAP4-16 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	III,IV	0.187	0.561	<.001	180	view →
KIRP	DFS	Tertile	III,IV	0.138	0.712	<.001	123	view →
ACC	DFS	Tertile	II,III,IV	0.046	0.732	<.001	72	view →
KIRC	DFS	Tertile	IV	0.038	0.632	<.001	36	view →
UCEC	OS	Tertile	All	0.849	0.929	.001	36	view →
SKCM	OS	Tertile	II,III,IV	0.190	0.739	.002	18	view →
COAD	DFS	Tertile	IV	0.028	0.496	<.001	18	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
LUSC	OS	Tertile	II,III,IV	0.196	0.615	.031	9	view →
SARC	DFS	Tertile	All	0.158	0.549	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

KRTAP4-16–BLCA (OS)

Open the BLCA breakdown →