Across TCGA patient cohorts, KRTAP4-1 mutation is significantly associated with the RNA expression of many other genes, with 723 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP4-1-associated genes across cancer lineages are HSPD1P18, RNU6-463P, and RPL23AP90. Each is linked with KRTAP4-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP4-1-to-partner and partner-to-KRTAP4-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP4-1→partner) and Y-score (partner→KRTAP4-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HSPD1P18 →	+0.308	+3.870	<.001	.006	3	2
HNSC	RNU6-463P →	+0.363	+7.954	<.001	.008	3	1
UCEC	RPL23AP90 →	+0.336	+1.975	.001	.007	3	1
UCEC	CCL5 →	+1.337	+3.928	<.001	<.001	3	1
UCEC	LINC02084 →	+0.475	+3.354	.002	.005	3	1
UCEC	RN7SL248P →	+0.080	+3.606	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 723 associations by consensus.

Exploration

KRTAP4-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP4-1 data types