Across TCGA patient cohorts, KRTAP3-3 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRTAP3-3-associated genes across cancer lineages are RNU6-526P, MIR6090, and RN7SL186P. Each is linked with KRTAP3-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP3-3-to-partner and partner-to-KRTAP3-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP3-3→partner) and Y-score (partner→KRTAP3-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-526P →	+0.897	+6.199	<.001	.001	3	2
SKCM	MIR6090 →	+0.594	+5.159	<.001	.007	3	1
SKCM	RN7SL186P →	+0.184	+5.224	<.001	.007	3	1
LUAD	RNU6-1244P →	+0.332	+7.930	<.001	.008	3	1
LUAD	RNU6-847P →	+0.333	+7.930	<.001	.008	3	1
SKCM	ANKRD26P2 →	+0.033	+5.362	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

KRTAP3-3 survival (RNA) · tumor vs normal (RNA) · all KRTAP3-3 data types