KRTAP26-1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP26-1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP26-1-associated genes across cancer lineages are ASNS, ATM, and eIF4G. Each is linked with KRTAP26-1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP26-1-to-partner and partner-to-KRTAP26-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP26-1→partner) and Y-score (partner→KRTAP26-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECASNS →+0.625+3.807<.001<.00133
UCECATM →-0.702-2.321<.001.00632
UCECeIF4G →+0.264+2.999.039.03531
UCECERK2 →+0.202+2.000.011.03031
UCECFoxM1 →+0.223+1.807.037.02731
UCECACC1 →+0.325+3.013.030.01831
Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration