Across TCGA patient cohorts, KRTAP23-1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP23-1-associated genes across cancer lineages are RN7SL205P, MIR133B, and MIR1258. Each is linked with KRTAP23-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP23-1-to-partner and partner-to-KRTAP23-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP23-1→partner) and Y-score (partner→KRTAP23-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SL205P →	+0.353	+4.990	<.001	.009	3	1
UCEC	MIR133B →	+0.356	+8.066	<.001	.007	3	1
UCEC	MIR1258 →	+0.509	+8.066	<.001	.007	3	1
UCEC	FAM243A →	+0.069	+8.066	<.001	.007	3	1
UCEC	RNU7-95P →	+0.562	+8.066	<.001	.007	3	1
UCEC	USP9YP2 →	+0.054	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

KRTAP23-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP23-1 data types