Across TCGA cell cohorts, KRTAP22-2 RNA expression is significantly associated with the mutation status of many other genes, with 80 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRTAP22-2-associated genes across cancer lineages are CAPN1, SPAG16, and CEP295. Each is linked with KRTAP22-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP22-2-to-partner and partner-to-KRTAP22-2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP22-2→partner) and Y-score (partner→KRTAP22-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CAPN1 →	+4.437	+0.100	.004	<.001	3	2
BLOOD_Myeloma	SPAG16 →	+4.807	+0.229	.006	<.001	3	1
BLOOD_Myeloma	CEP295 →	+4.807	+0.229	.006	<.001	3	1
BLOOD_Myeloma	KCNV2 →	+4.807	+0.229	.006	<.001	3	1
BLOOD_Myeloma	RGMB →	+4.807	+0.229	.006	<.001	3	1
BLOOD_Myeloma	CNR2 →	+4.807	+0.229	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

Exploration

KRTAP22-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP22-2 data types