KRTAP21-4P

Across TCGA pan-cancer cohorts, KRTAP21-4P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of KRTAP21-4P’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where KRTAP21-4P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP21-4P is over-expressed in tumor.

UCEC, COAD, and PRAD are the cancer types where KRTAP21-4P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP21-4P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.178	.039	2	view →
COAD	All	All	+0.061	.024	2	view →
PRAD	All	All	+0.008	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

KRTAP21-4P–UCEC

Open the UCEC breakdown →