Across TCGA patient cohorts, KRTAP2-2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP2-2-associated genes across cancer lineages are IGKV2OR2-10, TERF1P1, and OR12D2. Each is linked with KRTAP2-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP2-2-to-partner and partner-to-KRTAP2-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP2-2→partner) and Y-score (partner→KRTAP2-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV2OR2-10 →	+0.198	+4.937	<.001	.005	3	1
UCEC	TERF1P1 →	+0.080	+4.484	<.001	.009	3	1
UCEC	OR12D2 →	+0.040	+4.771	.004	.006	3	1
UCEC	MIR425 →	+0.634	+4.499	.007	.005	3	1
UCEC	RNU6-1233P →	+0.477	+5.722	.009	.001	3	1
UCEC	RNU6-1082P →	+0.441	+4.551	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

KRTAP2-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP2-2 data types