Across TCGA patient cohorts, KRTAP2-1 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP2-1-associated genes across cancer lineages are RN7SL803P, RN7SL248P, and MIR4999. Each is linked with KRTAP2-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP2-1-to-partner and partner-to-KRTAP2-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP2-1→partner) and Y-score (partner→KRTAP2-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL803P →	+0.314	+3.413	.007	.006	3	1
UCEC	RN7SL248P →	+0.145	+4.722	<.001	.004	3	1
UCEC	MIR4999 →	+0.734	+3.885	.004	.004	3	1
UCEC	MIR4287 →	+0.458	+5.245	<.001	.002	3	1
UCEC	ZNF92P2 →	+0.079	+3.599	.002	.007	3	1
UCEC	TERF1P2 →	+0.146	+4.137	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

KRTAP2-1 survival (RNA) · tumor vs normal (RNA) · all KRTAP2-1 data types