KRTAP19-7

Across TCGA patient cohorts, KRTAP19-7 mutation is significantly associated with the RNA expression of many other genes, with 155 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP19-7-associated genes across cancer lineages are RNA5SP35, POLE2, and NDUFAF5. Each is linked with KRTAP19-7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP19-7-to-partner and partner-to-KRTAP19-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP35 grouped by KRTAP19-7-low versus KRTAP19-7-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP19-7→partner) and Y-score (partner→KRTAP19-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP35 →	+0.844	+5.798	<.001	.003	3	2
UCEC	POLE2 →	+0.828	+3.191	.001	.009	3	1
UCEC	NDUFAF5 →	+0.447	+3.245	.005	.009	3	1
UCEC	CMC2 →	+0.601	+3.202	<.001	.009	3	1
UCEC	BCCIP →	+0.565	+3.222	.006	.009	3	1
UCEC	RNF43 →	+1.362	+3.201	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 155 associations by consensus.

RNA5SP35 by KRTAP19-7 expression — LUAD

Explore this box plot interactively →