KRTAP19-7

Across TCGA pan-cancer cohorts, KRTAP19-7 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated KRTAP19-7 data layer compared with 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher KRTAP19-7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP19-7 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LAML show a favorable association.

LUSC, STAD, and LIHC are the cancer types where KRTAP19-7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	III,IV	0.115	0.691	<.001	63	view →
STAD	OS	Tertile	II,III,IV	0.277	0.725	<.001	60	view →
LIHC	DFS	Tertile	All	0.129	0.549	<.001	54	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
LGG	OS	Tertile	All	0.530	0.814	.009	24	view →
ESCA	OS	Tertile	III,IV	0.829	0.357	.025	18	view →
PRAD	OS	Tertile	All	0.869	0.990	<.001	18	view →
PCPG	DFS	Tertile	All	0.365	0.854	.001	18	view →
SKCM	DFS	Tertile	II,III,IV	0.200	0.566	.005	18	view →
LAML	DFS	Tertile	All	1.000	0.358	.048	12	view →
THCA	DFS	Tertile	II,III,IV	0.161	0.732	.036	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

KRTAP19-7–LUSC (OS)

Open the LUSC breakdown →