KRTAP19-7

Across TCGA patient cohorts, KRTAP19-7 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP19-7-associated genes across cancer lineages are eIF4G, FoxM1, and MIG-6. Each is linked with KRTAP19-7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP19-7-to-partner and partner-to-KRTAP19-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4G grouped by KRTAP19-7-low versus KRTAP19-7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP19-7→partner) and Y-score (partner→KRTAP19-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4G →	+0.366	+3.000	.031	.036	3	1
UCEC	FoxM1 →	+0.412	+2.817	.003	.036	3	1
UCEC	MIG-6 →	+0.122	+3.183	.025	.010	3	1
UCEC	Notch1 →	+0.178	+3.169	.021	.020	3	1
UCEC	Rictor_pT1135 →	-0.128	-3.000	.023	.036	3	1
UCEC	14-3-3_beta →	-0.128	-3.156	.020	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

eIF4G by KRTAP19-7 expression — UCEC

Explore this box plot interactively →