Across TCGA pan-cancer cohorts, KRTAP19-6 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of KRTAP19-6’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where KRTAP19-6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP19-6 is over-expressed in tumor.
UCEC are the cancer types where KRTAP19-6 tumor–normal differential expression is most reproducible.