KRTAP19-3

Across TCGA patient cohorts, KRTAP19-3 mutation is significantly associated with the RNA expression of many other genes, with 1,485 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP19-3-associated genes across cancer lineages are MIR7702, PPIAP24, and OR5B17. Each is linked with KRTAP19-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP19-3-to-partner and partner-to-KRTAP19-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by KRTAP19-3-low versus KRTAP19-3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP19-3→partner) and Y-score (partner→KRTAP19-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.309	+4.738	<.001	.002	3	2
HNSC	PPIAP24 →	+0.181	+4.240	<.001	.003	3	2
HNSC	OR5B17 →	+0.040	+4.636	.001	.006	3	2
LUAD	RPSAP23 →	+0.069	+4.399	.001	.006	3	2
HNSC	NDUFA5P4 →	+0.070	+4.526	<.001	.007	3	2
UCEC	RNA5SP408 →	+0.308	+3.186	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,485 associations by consensus.

MIR7702 by KRTAP19-3 expression — UCEC

Explore this box plot interactively →