KRTAP19-3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP19-3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP19-3-associated genes across cancer lineages are GMP, Chondrocytes, and Sebocytes. Each is linked with KRTAP19-3 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP19-3-to-partner and partner-to-KRTAP19-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by KRTAP19-3-low versus KRTAP19-3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP19-3→partner) and Y-score (partner→KRTAP19-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCGMP →+0.125+3.654<.001.00933
LUSCChondrocytes →+0.020+3.109<.001.04331
UCECSebocytes →-0.027-2.300.030.03631
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GMP by KRTAP19-3 expression — HNSC

Box plot of GMP in KRTAP19-3-low vs KRTAP19-3-high samples in HNSC.

Explore this box plot interactively →

Exploration