KRTAP15-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP15-1 mutation is significantly associated with the RNA expression of many other genes, with 129 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KRTAP15-1-associated genes across cancer lineages are TXNP3, TUBB4BP1, and ATP6V1E1P2. Each is linked with KRTAP15-1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRTAP15-1-to-partner and partner-to-KRTAP15-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP15-1→partner) and Y-score (partner→KRTAP15-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCTXNP3 →+0.217+4.715<.001.00333
COADTUBB4BP1 →+0.255+4.917<.001.00332
UCECATP6V1E1P2 →+0.244+3.398<.001.00132
SKCMFTH1P9 →+0.059+5.906<.001<.00132
UCECRNU4-13P →+0.145+4.242<.001.00632
LUADIQCF6 →+0.288+2.967.002.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 129 associations by consensus.

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