Across TCGA pan-cancer cohorts, KRTAP13-4 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KRTAP13-4 data layer compared with 10 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher KRTAP13-4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP13-4 expression acts as an unfavorable survival marker.

COAD, SARC, and LUSC are the cancer types where KRTAP13-4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.001	0.871	<.001	12	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
LUSC	OS	Median	All	0.180	0.518	.008	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: KRTAP13-4 tumor-vs-normal RNA expression · all KRTAP13-4 data types