Across TCGA pan-cancer cohorts, KRTAP13-4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of KRTAP13-4’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where KRTAP13-4 RNA is repressed in tumor relative to normal tissue. In most cancer types KRTAP13-4 is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

BRCA, LUAD, and LUSC are the cancer types where KRTAP13-4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP13-4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.383	<.001	8	view →
LUAD	Female	All	−0.061	.001	2	view →
LUSC	All	All	−0.028	.020	1	view →
THCA	All	All	−0.016	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: KRTAP13-4 RNA expression & survival · all KRTAP13-4 data types