Across TCGA cell cohorts, KRTAP13-4 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRTAP13-4-associated genes across cancer lineages are WFDC12, DEFB4A, and CFHR2. Each is linked with KRTAP13-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP13-4-to-partner and partner-to-KRTAP13-4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP13-4→partner) and Y-score (partner→KRTAP13-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	WFDC12 →	+0.249	+4.874	<.001	.002	3	1
BLOOD_Leukemia	DEFB4A →	+0.123	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1
LUNG_NSCLC_LUAD	RXFP2 →	+0.030	+4.959	.005	<.001	3	1
LUNG_NSCLC_LUAD	PSKH2 →	+0.022	+4.472	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

KRTAP13-4 survival (RNA) · tumor vs normal (RNA) · all KRTAP13-4 data types