KRTAP13-3

Across TCGA patient cohorts, KRTAP13-3 mutation is significantly associated with the RNA expression of many other genes, with 1,346 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP13-3-associated genes across cancer lineages are ETDB, P2RY10BP, and RNU6-1213P. Each is linked with KRTAP13-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP13-3-to-partner and partner-to-KRTAP13-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETDB grouped by KRTAP13-3-low versus KRTAP13-3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP13-3→partner) and Y-score (partner→KRTAP13-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ETDB →	+0.058	+5.912	<.001	.002	3	2
HNSC	P2RY10BP →	+0.086	+5.912	<.001	.002	3	2
HNSC	RNU6-1213P →	+0.720	+6.221	<.001	.001	3	2
HNSC	IGKV2-36 →	+0.233	+5.435	<.001	.005	3	2
LUAD	MIR3928 →	+0.630	+4.285	<.001	.003	3	2
READ	IGHD5-12 →	+1.742	+5.421	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,346 associations by consensus.

ETDB by KRTAP13-3 expression — HNSC

Explore this box plot interactively →