Across TCGA patient cohorts, KRTAP13-2 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP13-2-associated genes across cancer lineages are mTOR_pS2448, Tuberin, and VHL. Each is linked with KRTAP13-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP13-2-to-partner and partner-to-KRTAP13-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP13-2→partner) and Y-score (partner→KRTAP13-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.173	-3.150	.021	.019	3	1
UCEC	Tuberin →	+0.286	+3.009	.035	.019	3	1
UCEC	VHL →	-0.747	-3.000	.028	.036	3	1
UCEC	Bak →	+0.298	+3.000	.017	.036	3	1
UCEC	Cyclin-B1 →	+0.694	+3.459	.013	.005	3	1
UCEC	Ku80 →	+0.270	+2.335	.022	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

KRTAP13-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP13-2 data types