Across TCGA pan-cancer cohorts, KRTAP13-1 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated KRTAP13-1 data layer compared with 10 for mass-spec protein.
The strongest signal is observed in small cell lung cancer (SCLC), where higher KRTAP13-1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KRTAP13-1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and COAD show a favorable association.
SCLC, ACC, and SKCM are the cancer types where KRTAP13-1 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.